ESGE Endorsed research projects

Project	Leader	Country
Clinical vAliDation of ARTificial Intelligence in colorectal POlyp Detection	P. Sinonquel	Belgium
Digital images of fine needle biopsy of solid pancreatic lesions created by fluorescence confocal microscopy: inter-observer agreement between pathologists	F. M. Di Mateo	Italy
Biliary Papillomatosis: Endoscopic Findings, Treatment and Outcomes. An International Multicenter Analysis	M. Bronswijk	Belgium
Towards painless colonoscopy: a dedicated training to decrease the rate of painful colonoscopy – a randomized controlled trial	M. Szmit	Poland
Development of a new medical device for the endoscopic treatment of post-surgical fistulas of the GI-tract	V. Lorenzo - Zúñiga García	Spain
European practice and outcome of Endoscopy for Chronic Pancreatitis (ESCOPA): A Prospective, International Modified Snapshot Study*	R. P. Voermans	The Netherlands
EMR vs ESD for Large colorectal LSTs. A non inferiority RCT*	E. Ulloa Márquez	Spain

*Studies that are currently seeking participants. Please click on the name of the study for details.

Information:	esperanza.ulloa@salud.madrid.org
Synopsis of the project:	EMR and ESD are both effective and safe and are associated with a very low risk of procedure related mortality when performed for colorectal laterally spreading lesions (LSL). Some kind of LSLs have a low risk of submucosal invasive carcinoma (SMIC) or these foci are found in well demarcated areas of the tumor. This is the case of the non-granular flat elevated (LSN-NG-FE) and the LSLs-G mixed subtypes.The investigators aim to assess if piecemeal EMR (the older technique) for LSLs-G mixed type > 30 mm and LSLs-NG FE type > 20 mm is not inferior to ESD (the new treatment) for the need of additional surgery in the mid-term
Protocol:	https://drive.google.com/file/d/ 11sGy8og3zy86NaKGWQRHIvauvAZmp_9F/ view?usp=sharing

Information:	escopa@amsterdamumc.nl
Synopsis of the project:	Indications for and strategies of endoscopic treatment in chronic pancreatitis (CP) vary between (expert) centers in Europe. Therefore, a Pan-European prospective modified snapshot study will be conducted between June 1 2021- May 31 2022 to evaluate practice variation of CP endoscopy across Europe and its influence on outcome. Every center in Europe can participate. Proof of IRB approval by the medical ethic committee of the Amsterdam UMC is available. For ESCOPA 1, primary endpoint is technical success defined as successful endoscopic removal of a stone and/or successful placement of a pancreatic duct (PD) stent across a PD stricture (follow up 6 months). For ESCOPA 2 the primary endpoint is pain, assessed by the Izbicki pain score (follow up 24 month).
Protocol:	https://docs.google.com/ document/d/ 1TMO5Wf8p4P7RZ0aMXwCQ_M40 3zY3cSfKY8SU8GuHcJ0 /edit?usp=sharing
Registration:	https://docs.google.com / forms/d/e/ 1FAIpQLSeJQlsIbwe2d LZ8k7NsQ0XbCIG4Sh-CvSWC7 pgMmMsNOWur0Q/viewform?usp=sf_link)